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Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the big blue transgenic mouse.

The aromatic amines 2,4-diaminotoluene (2,4-DAT) and 2,6-diaminotoluene (2,6-DAT) are structural isomers that have been extensively studied for their mutagenic and carcinogenic characteristics. Both compounds are rapidly absorbed after oral administration and are equally mutagenic in the Ames test;...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cunningham, M L, Hayward, J J, Shane, B S, Tindall, K R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1469641/
https://ncbi.nlm.nih.gov/pubmed/8781405
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