A new method of synthesis of fluorescently labelled oligonucleotides and their application in DNA sequencing.

A new approach to the chemical synthesis of oligodeoxynucleotides bearing reporter functional groups at base residues of 3'-end nucleosides is reported. Applications of the 3'-end fluorescently labelled primers for automated DNA sequencing are shown.

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Detalhes bibliográficos
Main Authors: Markiewicz, W T, Gröger, G, Rösch, R, Zebrowska, A, Markiewicz, M, Klotz, M, Hinz, M, Godzina, P, Seliger, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146946/
https://ncbi.nlm.nih.gov/pubmed/9278489
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