A new method of synthesis of fluorescently labelled oligonucleotides and their application in DNA sequencing.

A new approach to the chemical synthesis of oligodeoxynucleotides bearing reporter functional groups at base residues of 3'-end nucleosides is reported. Applications of the 3'-end fluorescently labelled primers for automated DNA sequencing are shown.

Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Markiewicz, W T, Gröger, G, Rösch, R, Zebrowska, A, Markiewicz, M, Klotz, M, Hinz, M, Godzina, P, Seliger, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3672
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