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Genetic evidence for selective degradation of RNA polymerase subunits by the 20S proteasome in Saccharomyces cerevisiae.

scs32 was isolated as an extragenic suppressor of a temperature-sensitive (ts) mutation (rpo26-31) in the gene encoding Rpo26p, a subunit common to yeast nuclear RNA polymerases (RNAPs). rpo26-31 also confers inositol auxotrophy, inhibits the assembly of RNAPI and RNAPII and reduces the steady-state...

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Udgivet i:Nucleic Acids Res
Principais autores: Nouraini, S, Xu, D, Nelson, S, Lee, M, Friesen, J D
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146930/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3570
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