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Phospholipase A2 is involved in the mechanism of activation of neutrophils by polychlorinated biphenyls.

Aroclor 1242, a mixture of polychlorinated biphenyls (PCBs), activates neutrophils to produce superoxide anion (O2-) by a mechanism that involves phospholipase C-dependent hydrolysis of membrane phosphoinositides; however, subsequent signal transduction mechanisms are unknown. We undertook this stud...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tithof, P K, Schiamberg, E, Peters-Golden, M, Ganey, P E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1469247/
https://ncbi.nlm.nih.gov/pubmed/8834862
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