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The role of a basic amino acid cluster in target site selection and non-specific binding of bZIP peptides to DNA.

The ability of a transcription factor to locate and bind its cognate DNA site in the presence of closely related sites and a vast array of non-specific DNA is crucial for cell survival. The CREB/ATF family of transcription factors is an important group of basic region leucine zipper (bZIP) proteins...

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Pubblicato in:Nucleic Acids Res
Autori principali: Metallo, S J, Paolella, D N, Schepartz, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9224594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.15.2967
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