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Identification of an intronic enhancer that nullifies upstream repression of SPARC gene expression.

The SPARC gene 5'flanking sequence has been shown to contain enhancer elements, but also negative control elements immediately upstream of the enhancer elements. Although these 5'enhancer elements are active in F9 and PYS-2 cells, their activities are nullified by the 5'repressor activity. In the pr...

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Udgivet i:Nucleic Acids Res
Principais autores: Satyamoorthy, K, Samulewicz, S J, Thornburg, L D, Basu, A, Howe, C C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9224620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.15.3169
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