Complementation of the DNA repair-deficient swi10 mutant of fission yeast by the human ERCC1 gene.
In human cells DNA damage caused by UV light is mainly repaired by the nucleotide excision repair pathway. This mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incis...
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| Опубліковано в:: | Nucleic Acids Res |
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| Автори: | , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Oxford University Press
1997
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.14.2823 |
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