Formation of a G-tetrad and higher order structures correlates with biological activity of the RelA (NF-kappaB p65) 'antisense' oligodeoxynucleotide.

We have examined the behavior of the phosphorothioate antisense Rel A (NF-kappaB p65) oligodeoxynucleotide (oligo) and related molecules. Because of the presence of a G-tetrad near its 5'terminus, this molecule is capable of forming tetraplexes and other higher order structures in a temperature and...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Benimetskaya, L, Berton, M, Kolbanovsky, A, Benimetsky, S, Stein, C A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9185577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.13.2648
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