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Evolutionarily conserved and functionally important residues in the I-CeuI homing endonuclease.

Two approaches were used to discern critical amino acid residues for the function of the I- Ceu I homing endonuclease: sequence comparison of subfamilies of homologous proteins and genetic selection. The first approach revealed residues potentially involved in catalysis and DNA recognition. Because...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Turmel, M, Otis, C, Côté, V, Lemieux, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146779/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9185572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.13.2610
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