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De novo design and characterization of an apolar helical hairpin peptide at atomic resolution: Compaction mediated by weak interactions

Design of helical super secondary structural motifs is expected to provide important scaffolds to incorporate functional sites, thus allowing the engineering of novel miniproteins with function. An α,β-dehydrophenylalanine containing 21-residue apolar peptide was designed to mimic the helical hairpi...

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Detalhes bibliográficos
Main Authors: Ramagopal, Udupi A., Ramakumar, Suryanarayanarao, Sahal, Dinkar, Chauhan, Virander S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14676/
https://ncbi.nlm.nih.gov/pubmed/11158562
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