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Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression.

Mutations in the ATM gene are responsible for the multisystem disorder ataxia-telangiectasia, characterized by neurodegeneration, immune deficiency and cancer predisposition. While no alternative splicing was identified within the coding region, the first four exons of the ATM gene, which fall withi...

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Udgivet i:Nucleic Acids Res
Principais autores: Savitsky, K, Platzer, M, Uziel, T, Gilad, S, Sartiel, A, Rosenthal, A, Elroy-Stein, O, Shiloh, Y, Rotman, G
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146671/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108147/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.9.1678
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