The mechanism of mutation induction by a hydrogen bond ambivalent, bicyclic N4-oxy-2'-deoxycytidine in Escherichia coli.

The triphosphate of the nucleoside deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one (dP) is known to be incorporated into DNA efficiently by Taq polymerase and is a useful tool for polymerase-mediated in vitro mutagenesis. It is shown here that dP is a potent mutagen in Escherichia coli and Salm...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Negishi, K, Williams, D M, Inoue, Y, Moriyama, K, Brown, D M, Hayatsu, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146628/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9092660/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.8.1548
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