c-Myc/Max heterodimers bind cooperatively to the E-box sequences located in the first intron of the rat ornithine decarboxylase (ODC) gene.

The oncoprotein c-Myc plays an important role in cell proliferation, transformation, inhibition of differentiation and apoptosis. These functions most likely result from the transcription factor activity of c-Myc. As a heterodimer with Max, the c-Myc protein binds to the E-box sequence (CACGTG), whi...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Walhout, A J, Gubbels, J M, Bernards, R, van der Vliet, P C, Timmers, H T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9162900/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.8.1493
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