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Cysteine-to-alanine replacements in the Escherichia coli SoxR protein and the role of the [2Fe-2S] centers in transcriptional activation.

The Escherichia coli soxRS regulon activates oxidative stress and antibiotic resistance genes in two transcriptional stages. SoxR protein becomes activated in cells exposed to excess superoxide or nitric oxide and then stimulates transcription of the soxS gene, whose product in turn activates>/=10 r...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Bradley, T M, Hidalgo, E, Leautaud, V, Ding, H, Demple, B
Format: Artigo
Language:Inglês
Published: Oxford University Press 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146616/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9092651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.8.1469
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