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A muscle-specific enhancer within intron 1 of the human dystrophin gene is functionally dependent on single MEF-1/E box and MEF-2/AT-rich sequence motifs.

In previous studies we have described a 5.0 kb Hin dIII fragment downstream of muscle exon 1 that exhibits properties consistent with a muscle-specific transcriptional enhancer. The goal of this study has been to identify the sequence elements responsible for muscle-specific enhancer activity. Funct...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Klamut, H J, Bosnoyan-Collins, L O, Worton, R G, Ray, P N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9092671/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.8.1618
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