Mechanisms of triplex-caused polymerization arrest.

Pyrimidine/purine/purine triplexes are known to inhibit DNA polymerization. Here we have studied the mechanisms of this inhibition by comparing the efficiency of Vent DNA polymerase on triplex- and duplex-containing templates at different temperatures, Mg2+concentrations and time intervals with the...

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Bibliographic Details
Main Authors: Krasilnikov, A S, Panyutin, I G, Samadashwily, G M, Cox, R, Lazurkin, Y S, Mirkin, S M
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC146602/
https://ncbi.nlm.nih.gov/pubmed/9060427
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