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Covalent attachment of DNA oligonucleotides to glass.

A method for synthesizing DNA directly on glass is presented. The process is based on pretreatment of glass with boiling hydrochloric acid, thus exposing the hydroxyl groups of the glass. Phosphite-triester chemistry was used to directly attach the first nucleotide to a glass plate via a covalent bo...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Cohen, G, Deutsch, J, Fineberg, J, Levine, A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146495/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.4.911
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