Molecular basis of artifacts in the detection of telomerase activity and a modified primer for a more robust 'TRAP' assay.

Human somatic cells have essentially no telomerase activity. Telomerase is linked to tumor genesis and is a valuable marker for malignant growth. Extreme paucity of the enzyme neccessitated development of a PCR-based assay, 'telomeric repeat amplification protocol' (TRAP). Unfortunately, t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Krupp, G, Kühne, K, Tamm, S, Klapper, W, Heidorn, K, Rott, A, Parwaresch, R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1997
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC146494/
https://ncbi.nlm.nih.gov/pubmed/9016650
Tagiau: Ychwanegu Tag
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