Structural analysis of mouse rDNA: coincidence between nuclease hypersensitive sites, DNA curvature and regulatory elements in the intergenic spacer.

We have analyzed the chromatin structure of mouse ribosomal RNA genes (rDNA) by partial digestion of genomic DNA with micrococcal nuclease (MNase), DNase I and identified hypersensitive sites by indirect end-labeling. This analysis has revealed defined regions of nuclease hypersensitivity in the int...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Längst, G, Schätz, T, Langowski, J, Grummt, I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016589/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.3.511
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