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tRNA(His) guanylyltransferase adds G(−1) to the 5′ end of tRNA(His) by recognition of the anticodon, one of several features unexpectedly shared with tRNA synthetases

All eukaryotic tRNA(His) molecules are unique among tRNA species because they require addition of a guanine nucleotide at the −1 position by tRNA(His) guanylyltransferase, encoded in yeast by THG1. This G(−1) residue is both necessary and sufficient for aminoacylation of tRNA by histidyl-tRNA synthe...

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Detalhes bibliográficos
Main Authors: Jackman, Jane E., Phizicky, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464847/
https://ncbi.nlm.nih.gov/pubmed/16625026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.54706
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