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Role of chloride channels in bradykinin-induced guinea pig airway vagal C-fibre activation

We tested the hypothesis that an ionic current carried by chloride ions contributes to bradykinin (BK)-induced membrane depolarization and activation of vagal afferent C-fibres. In an ex vivo innervated trachea/bronchus preparation, BK (1 μm) consistently produced action potential discharge in vagal...

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Autori principali: Lee, Min-Goo, MacGlashan, Donald W, Undem, Bradley J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464732/
https://ncbi.nlm.nih.gov/pubmed/15860525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.087577
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