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Reduced α-adrenoceptor responsiveness and enhanced baroreflex sensitivity in Cry-deficient mice lacking a biological clock

To reveal the role of clock genes in generating the circadian rhythm of baroreflexes, we continuously measured mean arterial pressure and baroreflex sensitivity in free-moving normal wild-type mice, and in Cry-deficient mice which lack a circadian rhythm, in constant darkness for 24 h. In wild-type...

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Autori principali: Masuki, Shizue, Todo, Takeshi, Nakano, Yasushi, Okamura, Hitoshi, Nose, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464725/
https://ncbi.nlm.nih.gov/pubmed/15860530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.086728
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