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Behavioral sensitization to amphetamine results from an uncoupling between noradrenergic and serotonergic neurons

In rodents, drugs of abuse induce locomotor hyperactivity, and repeating injections enhances this response. This effect, called behavioral sensitization, persists many months after the last administration, thus mimicking long-term sensitivity to drugs observed in human addicts. We show here that, in...

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Detalles Bibliográficos
Main Authors: Salomon, Lucas, Lanteri, Christophe, Glowinski, Jacques, Tassin, Jean-Pol
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464364/
https://ncbi.nlm.nih.gov/pubmed/16648258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600839103
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