Effects of nitric oxide synthase inhibition by l-NAME on oxygen uptake kinetics in isolated canine muscle in situ

Nitric oxide (NO) has an inhibitory action on O(2) uptake (V˙(O(2))) at the level of the mitochondrial respiratory chain. The aim of this study was to evaluate the effects of NO synthase (NOS) inhibition on muscle V˙(O(2)) kinetics. Isolated canine gastrocnemius muscles in situ (n= 6) were studied d...

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Detalhes bibliográficos
Main Authors: Grassi, Bruno, Hogan, Michael C, Kelley, Kevin M, Howlett, Richard A, Gladden, L Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Integrative Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464191/
https://ncbi.nlm.nih.gov/pubmed/16081490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.090068
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