Cl(−)secretion in ATP-treated renal epithelial C7–MDCK cells is mediated by activation of P(2Y1) receptors, phospholipase A(2) and protein kinase A

This study examines the mechanism of P(2Y)-induced Cl(−) secretion in monolayers of C7–Madin–Darby canine kidney (MDCK) cells triggered by basolateral application of ATP and measured as transcellular short current (I(SC)). Both ATP-induced arachidonic acid (AA) synthesis and I(SC) in ATP-treated cel...

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Detalhes bibliográficos
Main Authors: Akimova, A Olga, Bourcier, Nathalie, Taurin, Sebastien, Bundey, Richard A, Grygorczyk, Konrad, Gekle, Michael, Insel, Paul A, Dulin, Nickolai O, Orlov, Sergei N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Cell Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464179/
https://ncbi.nlm.nih.gov/pubmed/16109726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.094375
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