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Plasma concentrations of nortriptyline and its 10-hydroxy metabolite in depressed patients--relationship to the debrisoquine hydroxylation metabolic ratio.

In 20 depressed patients treated with nortriptyline (NT) there was a significant relationship between the plasma concentration of NT and the debrisoquine metabolic ratio (rs = 0.77; P less than 0.01). (The debrisoquine test was performed after stopping NT treatment). This is in agreement with the hy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nordin, C, Siwers, B, Benitez, J, Bertilsson, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1985
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463875/
https://ncbi.nlm.nih.gov/pubmed/4027124
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