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Enalapril (MK421) activation in man: importance of liver status.

The in vitro conversion of enalapril (MK421) to enalaprilic acid (MK422) in human autopsy tissues was examined. MK422 was measured by radioimmunoassay. Human cadaver liver was the only tissue in which significant conversion was demonstrated. The esterase activity was stable after post mortem. Autops...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Larmour, I, Jackson, B, Cubela, R, Johnston, C I
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1985
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463833/
https://ncbi.nlm.nih.gov/pubmed/2988590
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