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Lack of inhibition of purine nucleoside phosphorylase and adenosine deaminase in patients treated with azathioprine.

Deficiency of the purine salvage enzymes purine nucleoside phosphorylase (PNP) and adenosine deaminase (ADA) are known causes of immunodeficiency. Evidence for inhibition of these enzymes was sought in 16 patients on azathioprine therapy by testing for deoxyguanosine (PNP deficiency) and deoxyadenos...

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Bibliografische gegevens
Hoofdauteurs: Maddocks, J L, Al-Safi, S A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1985
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463784/
https://ncbi.nlm.nih.gov/pubmed/3919749
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