Single-dose pharmacokinetic and pharmacodynamic comparison of polymer-matrix (Slow Trasicor) and Oros dosage forms in healthy volunteers

1 Oxprenolol was administered in single doses by mouth to healthy volunteers either in a polymer-matrix slow-release formulation (Slow Trasicor®) or in osmotic drug-delivery systems (oxprenolol Oros). Plasma oxprenolol concentrations and heart rates after exercise were measured. 2 Plasma concentrati...

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Autores principales: Bennett, P. N., Bennett, J., Bradbrook, I., Francis, J., John, V. A., Rogers, H., Turner, P., Warrington, S. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
Materias:
Oxprenolol Oros Studies
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463746/
https://ncbi.nlm.nih.gov/pubmed/4005119
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