The effects of age and smoking on the plasma protein binding of lignocaine and diazepam.

In 63 healthy ambulant subjects 18 to 88 years of age, the plasma protein binding of diazepam (principally bound to albumin) decreased with age. Diazepam binding in plasma correlated positively with plasma albumin concentration which also decreased with age. In contrast, the plasma protein binding o...

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Bibliographic Details
Main Authors: Davis, D, Grossman, S H, Kitchell, B B, Shand, D G, Routledge, P A
Format: Artigo
Language:Inglês
Published: 1985
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463710/
https://ncbi.nlm.nih.gov/pubmed/3986083
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