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Is N-acetylation of 5-aminosalicylic acid reversible in man?

In two healthy male subjects the disposition of deuterated N-(2H3) acetyl-5-aminosalicylic acid (d3-ac-5-AS) was investigated after a single rectal dose of 500 mg d3-ac-5-AS. Urine and plasma were analysed by h.p.l.c. and gas chromatography mass-spectrometry. Peak concentrations of around 0.5 microg...

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Hlavní autoři: Meese, C O, Fischer, C, Klotz, U
Médium: Artigo
Jazyk:Inglês
Vydáno: 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463621/
https://ncbi.nlm.nih.gov/pubmed/6487501
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