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The role of the intestinal microflora in the reductive metabolism of acenocoumarol in man.

Although the oral anticoagulant acenocoumarol (AC) is very effectively metabolized by the intestinal microflora to its amino metabolite, under clinical conditions this route of AC-disposition is of no importance because the compound is rapidly absorbed from its pharmaceutical application form. Only...

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Detalhes bibliográficos
Main Authors: Thijssen, H H, Baars, L G, Hazen, M J, Van den Bogaard, A E
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463511/
https://ncbi.nlm.nih.gov/pubmed/6487465
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