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Pharmacokinetics of valproic acid in the elderly.

The kinetics of a single oral dose of sodium valproate was studied in six healthy elderly patients (age 68-89 years) and six young control subjects (age 24-26 years). The profiles of total plasma valproic acid (VPA) concentrations were very similar in the elderly and in the young. Half-lives (15.3 +...

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Autors principals: Perucca, E, Grimaldi, R, Gatti, G, Pirracchio, S, Crema, F, Frigo, G M
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463439/
https://ncbi.nlm.nih.gov/pubmed/6430313
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