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Pethidine binding in whole blood: methodology and clinical significance.

A three-compartment equilibrium dialysis method was developed for the simultaneous and direct determination of drug binding in whole blood and in plasma and of the blood to plasma concentration ratio (b/p). The unbound fraction of pethidine in the blood of six healthy volunteers (0.63, s.d. 0.09, n...

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Detalhes bibliográficos
Main Authors: La Rosa, C, Morgan, D J, Mather, L E
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463408/
https://ncbi.nlm.nih.gov/pubmed/6721986
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