Inhibition of self-splicing group I intron RNA: high-throughput screening assays.

High-throughput screening assays have been developed to rapidly identify small molecule inhibitors targeting catalytic group I introns. Biochemical reactions catalyzed by a self-splicing group I intron derived from Pneumocystis carinii or from bacteriophage T4 have been investigated. In vitro bioche...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Mei, H Y, Cui, M, Sutton, S T, Truong, H N, Chung, F Z, Czarnik, A W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.24.5051
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