The sensitivity of human fibroblasts to N-acetoxy-2-acetylaminofluorene is determined by the extent of transcription-coupled repair, and/or their capability to counteract RNA synthesis inhibition.

Nucleotide excision repair (NER) mechanism is the major pathway responsible for the removal of a large variety of bulky lesions from the genome. Two different NER subpathways have been identified, i.e. the transcription-coupled and the global genome repair pathways. For DNA-damage induced by ultravi...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	van Oosterwijk, M F, Filon, R, Kalle, W H, Mullenders, L H, van Zeeland, A A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.23.4653
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