Synthesis of full-length oligonucleotides: cleavage of apurinic molecules on a novel support.
The synthesis of oligodeoxynucleotides is marred by several problems that contribute to the formation of defective molecules. This in turn seriously limits the usefulness of such reagents in DNA diagnostics, molecular cloning, DNA structural analysis and in antisense therapy. In particular, depurina...
Guardat en:
| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146293/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8972847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.23.4632 |
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