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XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro.

The DNA repair proteins XRCC1 and DNA ligase III are physically associated in human cells and directly interact in vitro and in vivo. Here, we demonstrate that XRCC1 is additionally associated with DNA polymerase-beta in human cells and that these polypeptides also directly interact. We also present...

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Publicat a:Nucleic Acids Res
Autors principals: Caldecott, K W, Aoufouchi, S, Johnson, P, Shall, S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8948628/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.22.4387
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