Genetic interactions between the RhoA and Stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis.

The Drosophila RhoA (Rho1) GTPase is essential for postembryonic morphogenesis of leg and wing imaginal discs. Mutations in RhoA enhance leg and wing defects associated with mutations in zipper, the gene encoding the heavy chain of nonmuscle myosin II. We demonstrate here that mutations affecting th...

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Autors principals: Bayer, Cynthia A, Halsell, Susan R, Fristrom, James W, Kiehart, Daniel P, von Kalm, Laurence
Format: Artigo
Idioma:Inglês
Publicat: 2003
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462831/
https://ncbi.nlm.nih.gov/pubmed/14668391
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