p53 regulates the minimal promoter of the human topoisomerase IIalpha gene.

DNA topoisomerase IIalpha is an essential enzyme for chromosome segregation during mitosis. Consistent with a cell division-specific role, the expression of the topoisomerase IIalpha gene is strongly influenced by the proliferation status of cells. The p53 protein is one of the most important regula...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Sandri, M I, Isaacs, R J, Ongkeko, W M, Harris, A L, Hickson, I D, Broggini, M, Vikhanskaya, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146283/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8948636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.22.4464
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