A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway.

The JAK/STAT pathway exerts pleiotropic effects on a wide range of developmental processes in Drosophila. Four key components have been identified: Unpaired, a secreted ligand; Domeless, a cytokine-like receptor; Hopscotch, a JAK kinase; and Stat92E, a STAT transcription factor. The identification o...

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Main Authors: Bach, Erika A, Vincent, Stephane, Zeidler, Martin P, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462825/
https://ncbi.nlm.nih.gov/pubmed/14668372
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