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High-affinity AKAP7δ–protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides
PKA (protein kinase A) is tethered to subcellular compartments by direct interaction of its regulatory subunits (RI or RII) with AKAPs (A kinase-anchoring proteins). AKAPs preferentially bind RII subunits via their RII-binding domains. RII-binding domains form structurally conserved amphipathic heli...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462715/ https://ncbi.nlm.nih.gov/pubmed/16483255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051970 |
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