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Simplified modelling of metabolic pathways for flux prediction and optimization: lessons from an in vitro reconstruction of the upper part of glycolysis

Explicit modelling of metabolic networks relies on well-known mathematical tools and specialized computer programs. However, identifying and estimating the values of the very numerous enzyme parameters inherent to the models remain a tedious and difficult task, and the rate equations of the reaction...

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Detalhes bibliográficos
Main Authors: Fiévet, Julie B., Dillmann, Christine, Curien, Gilles, de vienne, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462707/
https://ncbi.nlm.nih.gov/pubmed/16460310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051520
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