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Akt phosphorylates and suppresses the transactivation of retinoic acid receptor α
The transactivation of nuclear receptors is regulated by both ligand binding and phosphorylation. We previously showed that RARα (retinoic acid receptor α) phosphorylation by c-Jun N-terminal kinase contributes to retinoid resistance in a subset of NSCLC cells (non-small cell lung cancer cells), but...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462695/ https://ncbi.nlm.nih.gov/pubmed/16417524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051794 |
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