Sit4 phosphatase is functionally linked to the ubiquitin-proteasome system.

Using a synthetic lethality screen we found that the Sit4 phosphatase is functionally linked to the ubiquitin-proteasome system. Yeast cells harboring sit4 mutations and an impaired proteasome (due to pre1-1 pre4-1 mutations) exhibited defective growth on minimal medium. Nearly identical synthetic e...

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Autors principals: Singer, Thorsten, Haefner, Stefan, Hoffmann, Michael, Fischer, Michael, Ilyina, Julia, Hilt, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462641/
https://ncbi.nlm.nih.gov/pubmed/12930741
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