Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae.

Yeast strains harboring mutations in genes required for telomerase function (TLC1 and the EST genes) exhibit progressive shortening of telomeric DNA and replicative senescence. A minority of cells withstands loss of telomerase through RAD52-dependent amplification of telomeric and subtelomeric seque...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Lowell, Joanna E, Roughton, Alexander I, Lundblad, Victoria, Pillus, Lorraine
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2003
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462614/
https://ncbi.nlm.nih.gov/pubmed/12871903
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