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Inbreeding and the genetic complexity of human hypertension.

Considerable uncertainty exists regarding the genetic architecture underlying common late-onset human diseases. In particular, the contribution of deleterious recessive alleles has been predicted to be greater for late-onset than for early-onset traits. We have investigated the contribution of reces...

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Detalhes bibliográficos
Main Authors: Rudan, Igor, Smolej-Narancic, Nina, Campbell, Harry, Carothers, Andrew, Wright, Alan, Janicijevic, Branka, Rudan, Pavao
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462484/
https://ncbi.nlm.nih.gov/pubmed/12663539
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