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DIM-1, a novel immunoglobulin superfamily protein in Caenorhabditis elegans, is necessary for maintaining bodywall muscle integrity.

The UNC-112 protein is required during initial muscle assembly in C. elegans to form dense bodies and M-lines. Loss of this protein results in arrest at the twofold stage of embryogenesis. In contrast, a missense mutation in unc-112 results in viable animals that have disorganized bodywall muscle an...

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Bibliographic Details
Main Authors: Rogalski, Teresa M, Gilbert, Mary M, Devenport, Danelle, Norman, Kenneth R, Moerman, Donald G
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462474/
https://ncbi.nlm.nih.gov/pubmed/12663531
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