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The CBP co-activator stimulates E2F1/DP1 activity.

The cell cycle-regulating transcription factors E2F1/DP1 activate genes whose products are required for S phase progression. During most of the G1 phase, E2F1/DP1 activity is repressed by the retinoblastoma gene product RB, which directly contacts the E2F1 activation domain and silences it. The E2F1...

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Main Authors: Trouche, D, Cook, A, Kouzarides, T
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC146244/
https://ncbi.nlm.nih.gov/pubmed/8932363
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