Mutant membrane protein of the budding yeast spindle pole body is targeted to the endoplasmic reticulum degradation pathway.

Mutation of either the yeast MPS2 or the NDC1 gene leads to identical spindle pole body (SPB) duplication defects: The newly formed SPB is improperly inserted into the nuclear envelope (NE), preventing the cell from forming a bipolar mitotic spindle. We have previously shown that both MPS2 and NDC1...

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Bibliographic Details
Main Authors: McBratney, Susan, Winey, Mark
Format: Artigo
Language:Inglês
Published: 2002
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462292/
https://ncbi.nlm.nih.gov/pubmed/12399372
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